دانلود کتاب خارجی - دانلود رایگان کتاب لاتین PDF علمی

تعداد نتایج: 352

Radiology of Orthopedic Implants

By Sanjeev Agarwal, Gaurav Jyoti Bansal
Publisher: Springer, 2018-07-29
Pages: 194
Language: en
ISBN_13:9783319760094
ISBN_10:3319760092
Subject: Medical

Osseointegration of Orthopaedic Implants

$Osseointegration of Orthopaedic Implants helps product developers at orthopedic implant manufacturers enhance the effectiveness of orthopedic implants and reduce complications, particularly in patients with osteoporotic bones. The book's expert contributors provide cutting-edge information on the latest technologies and advances available. Biomaterial researchers can use the book for basic data in the further development of orthopedic implant materials with better osseointegration. Biomechanical researchers can review related challenges and concepts of osseointegration for use in the development of implants. The book is suitable for readers from academia and industry, bridging the knowledge gap between academic based researchers, industrial based engineers, and clinical based surgeons. Reviews and discusses all aspects of orthopedic implant osseointegration Provides conceptual implants for bone fracture fixation and joint replacement Offers novel ideas for the development of orthopedic implants with superior osseointegration$

جزئیات و درخواست

By Amirhossein Goharian
Publisher: Academic Press, 2019-03-16
Pages: 214
Language: en
ISBN_13:9780128133958
ISBN_10:0128133953
Subject: Technology & Engineering

Interactions of Bone with Orthopedic Implants and Possible Failures

جزئیات و درخواست

By Amirhossein Goharian, Ehsan Golkar
Publisher: Academic Press, 2022-07-20
Pages: 326
Language: en
ISBN_13:9780323954112
ISBN_10:0323954111
Subject: Science

Modularity of Orthopedic Implants

جزئیات و درخواست

By Donald E. Marlowe, Jack E. Parr, Michael B. Mayor
Publisher: ASTM International, 1997
Pages: 249
Language: en
ISBN_13:9780803124158
ISBN_10:0803124155
Subject: Artificial hip joints

Osseoconductive Surface Engineering for Orthopedic Implants

Biomaterials Engineering

جزئیات و درخواست

By Amirhossein Goharian
Publisher: Academic Press, 2021-01-26
Pages: 252
Language: en
ISBN_13:9780128189313
ISBN_10:0128189312
Subject: Technology & Engineering

Mechanical Testing of Orthopaedic Implants

جزئیات و درخواست

By Elizabeth Friis
Publisher: Woodhead Publishing, 2017-05-24
Pages: 270
Language: en
ISBN_13:9780081002841
ISBN_10:008100284X
Subject: Medical

Retrieval and Analysis of Orthopaedic Implants

Proceedings of a Symposium Held at the National Bureau of St...

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جزئیات و درخواست

By Allan Weinstein, Emanuel Horowitz, Arthur W. Ruff
1977
Pages: 144
Language: en
OTHER:UOM:39015077586926
Subject: Metals in surgery

Biocompatibility of Orthopedic Implants

جزئیات و درخواست

By David F. Williams
Publisher: Springer, 1982-09-16
Pages: 342
Language: en
OTHER:UCSC:32106005815680
Subject: Medical

Wear of Orthopaedic Implants and Artificial Joints

جزئیات و درخواست

By Saverio Affatato
Publisher: Elsevier, 2012-04-12
Pages: 448
Language: en
ISBN_13:9780857096128
ISBN_10:0857096125
Subject: Technology & Engineering

The Radiology of Orthopaedic Implants

An Atlas of Techniques and Assessment

جزئیات و درخواست

By Andrew A. Freiberg
2001
Pages: 280
Language: en
OTHER:UOM:39015050503492
Subject: Medical

Aseptic Loosening of Orthopedic Implants

Osteoclastogenesis Regulation and Potential Therapeutics

$Aseptic loosening is the main cause of failure of orthopedic prostheses. With no pharmaceuticals to prevent or mitigate periprosthetic bone degradation, a surgery to replace the loose implant with a new one is the only choice to restore patients’ function. Most studies on mechanisms for aseptic loosening investigate wear debris particle-induced osteolysis. However, pathological loading conditions around unstable implants can also trigger osteoclast differentiation and bone loss. In the first study, global gene expression changes induced by mechanical instability of implants, and by titanium particles were compared in a validated rat model for aseptic loosening. Microarray analysis showed that similar signaling pathways and gene expression patterns are involved in particle- and instability-induced periprosthetic osteolysis with an early onset innate immune response as a hallmark of osteolysis induced by mechanical instability. Further, effects of potential therapeutics on restriction of excessive osteoclast differentiation were evaluated. Wnt signaling pathway is known to regulate bone remodeling. In the second study, effects of inactivation of glycogen synthase kinase 3 beta (GSK-3?), a negative regulator of canonical Wnt signaling, on instability-induced periprosthetic osteolysis were examined using our rat model for aseptic loosening. Inhibition of GSK-3? led to a decrease in osteoclast numbers in the periprosthetic bone tissue exposed to mechanical instability while osteoblast perimeter showed an increase. This was accompanied by higher bone volume fraction (BV/TV) in animals treated with the GSK-3? inhibitor. In the third study, potential beneficial effects of two selective inhibitors of cyclindependent kinase 8/19 (CDK8/19) on bone tissue were evaluated. CDK8/19 is a Mediator complex-associated transcriptional regulator involved in several signaling pathways. CDK8/19 inhibitors, mainly under investigation as treatments for tumors, are reported to enhance osteoblast differentiation and bone formation. We show in this study, for the first time, that inhibition of CDK8/19 led to marked suppression of osteoclast differentiation from bone marrow macrophages in vitro through disruption of the RANK signaling. In mouse primary osteoblasts downregulation of osteopontin mRNA, a negative regulator of mineralization, together with increased alkaline phosphatase activity and calcium deposition indicated that osteoblast mineralization was promoted by CDK8/19 inhibition. Moreover, local administration of a CDK8/19 inhibitor promoted cancellous bone regeneration in a rat model for bone healing. These studies contribute to better understanding of mechanisms behind mechanical instability-induced periprosthetic osteolysis and propose potential therapeutics to restrict bone loss with effects on both osteoclasts and osteoblasts.$

جزئیات و درخواست

By Mehdi Amirhosseini
Publisher: Linköping University Electronic Press, 2019-05-24
Pages: 41
Language: en
ISBN_13:9789176852385
ISBN_10:9176852385

Orthopedic Biomaterials

Progress in Biology, Manufacturing, and Industry Perspective...

جزئیات و درخواست

By Bingyun Li, Thomas Webster
Publisher: Springer, 2018-08-17
Pages: 496
Language: en
ISBN_13:9783319895420
ISBN_10:3319895427
Subject: Medical

Materials Sciences and Implant Orthopedic Surgery

$Combining experts from the medical and materials sciences, the Institute considered current concepts in medical and materials sciences as they relate to implantable prostheses in orthopedic surgical practice. The syllabus included theory and applications of materials properties, physiological function, and host response to metal and non-metal materials. Total hip prostheses are the most common orthopedic device implanted today involved in over 200,000 operations. Failures occur at the rate of 10~-40~ at ~ to 10 years. Failures are due to loosening, infection, fracture of femoral components, or destruction of the pe 1 vi c components .' All these, and other problems related to the implantation of the devices, the surgical procedures, and device pathology, were. discussed in light of current, as well as, emerging technologies and scientific knowledge. Repeatedly, scientists designing prostheses became aware of a lack of understanding of physiological phenomena associated with biocompatibility; the interchange among practising physicians, basic scientists, and pathologists at this Institute was appreciated. We thank all the contributors and participants for their effort. Thanks are also due to the personnel of the Scientific Affairs Division of NATO. The daily routines of running the Institute were greatly facilitated by the efforts of Pedro Cuevas, M.D, Jose Gutierrez Diaz, M.D, and Dr. Hanita Kossowsky. The devoted help of Nir Kossovsky, M.D, in setting the conference and in editing this book, is sincerely appreci ated.$

جزئیات و درخواست

By R. Kossowsky, Nir Kossovsky
Publisher: Springer Science & Business Media, 2012-12-06
Pages: 408
Language: en
ISBN_13:9789400944749
ISBN_10:9400944748
Subject: Science

Bone-Implant Interface in Orthopedic Surgery

Basic Science to Clinical Applications

جزئیات و درخواست

By Theofilos Karachalios
Publisher: Springer Science & Business Media, 2013-11-19
Pages: 342
Language: en
ISBN_13:9781447154099
ISBN_10:1447154096
Subject: Medical

BIOCOMPATIBILITY OF ORTHOPEDIC IMPLANTS VOL II

جزئیات و درخواست

By David Franklyn Williams
Publisher: Springer, 1982-10-08
Pages: 272
Language: en
OTHER:UCSC:32106005830580
Subject: Medical

Biomaterials In Orthopaedic Surgery

جزئیات و درخواست

By Federico Ángel Rodríguez-González
Publisher: ASM International, 2009-01-01
Pages: 237
Language: en
ISBN_13:9781615031290
ISBN_10:1615031294
Subject: Science

Biomaterials in Orthopedics

جزئیات و درخواست

By Michael J. Yaszemski
Publisher: CRC Press, 2003-10-17
Pages: 465
Language: en
ISBN_13:9780824756864
ISBN_10:082475686X
Subject: Medical

Advances in Materials Science and Implant Orthopedic Surgery

جزئیات و درخواست

By R. Kossowsky, Nir Kossovsky
Publisher: Springer Science & Business Media, 2012-12-06
Pages: 319
Language: en
ISBN_13:9789401101578
ISBN_10:9401101574
Subject: Technology & Engineering

Trauma Plating Systems

Biomechanical, Material, Biological, and Clinical Aspects

$Trauma Plating Systems is the first reference and systematic book in the topic of trauma plating system in view of biomechanical, material, biological, and clinical aspects. The effects of these aspects on effectiveness of trauma plating fixation are deeply reviewed, discussed, and challenged from which promising evaluation and development concepts are explored. This book is divided into five sections: Section I covers general concepts of biomechanical, material, biological, and clinical aspects. Then it provides fundamentals of trauma plating systems, principles of biomechanical evaluation methods, and biomechanics of plating fixation in Section II. Section III reviews current metallic materials with their advantages and disadvantages in plating fixation of bone fractures and new promising materials with their potential benefits to enhance the effectiveness of plating fixation. Section IV represents currently concerned biomechanical-clinical challenges of plating fixation for various bone fractures, and Section V presents current and new development concepts of this type of trauma implants. This book as an accessible and easy usable textbook for various disciplines of audiences who are dealing with trauma plating system and fixation such as orthopedic surgeons, trauma implant manufacturers, biomechanical researchers, biomaterial researchers, and all biomedical or medical students and residents in different levels of education. Author has been diligent in both engineering and research environments in terms of research, testing, analysis, validation, verification, clinical studies, and technical writing. His main interest and effort is to integrate biomechanical, material, biological, and clinical requirements of orthopedic implants for creation of novel design conception in this industry. He has developed the website http://orthoimplant-development.com/ for further communication in development of orthopedic implants. Smooth writing style for effective following, fast reading, and easy accessibility of the content Detailed and insight reviews, discussions, and new ideas in evaluation methods and design conception Disclosing of a novel conceptual plating system (Advance Healing Fixation System—AHealFS) with advanced biomechanical and clinical benefits in various stages of healing period potential to bring an interesting science breakthrough in fixation of bone fractures$

جزئیات و درخواست

By Amirhossein Goharian, Mohammed Rafiq Abdul Kadir, Mohamed Ruslan Abdullah
Publisher: Elsevier, 2017-03-15
Pages: 420
Language: en
ISBN_13:9780128047583
ISBN_10:0128047585
Subject: Technology & Engineering

Handbook of Orthopaedic Trauma Implantology

$This reference work comprehensively covers essential orthopedic trauma implants and their application in both upper and lower limbs. It offers insights into the invention, advantages, and disadvantages of various implants, along with the rationale behind their current designs, biomechanics, and materials. Additionally, the book addresses fracture fixation and general considerations when comparing different subgroups of implants, such as nails versus plates or ORIF versus external fixation. The book is divided into several sections, such as upper and lower limbs, spine, and pelvis. It also includes unique sections dedicated to pediatric implants, implant removal, metallurgy and bone grafts. It is written and edited by experienced surgeons from around the world. This book fills the gap as currently, there are no specific reference books on this topic but only operative manuals and inventory lists of various commercial companies detailing their own products. This highly informative and meticulously presented book serves as both a practical and a theoretical guide for practicing orthopedic surgeons, scientists/researchers, academicians, students as well as orthopedic technicians and nurses.$

جزئیات و درخواست

By Arindam Banerjee, Peter Biberthaler, Saseendar Shanmugasundaram
Publisher: Springer Nature, 2023-10-31
Pages: 2142
Language: en
ISBN_13:9789811975400
ISBN_10:981197540X
Subject: Medical

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