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تعداد نتایج: 341

Skeletal Aging and Osteoporosis

Biomechanics and Mechanobiology

$The focus of this book is on mechanical aspects of skeletal fragility related to aging and osteoporosis. Topics include: Age-related changes in trabecular structure and strength; age-related changes in cortical material properties; age-related changes in whole-bone structure; predicting bone strength and fracture risk using image-based methods and finite element analysis; animal models of osteoporosis and aging; age-related changes in skeletal mechano responsiveness; exercise and physical interventions for osteoporosis.$

جزئیات و درخواست

By Matthew J. Silva
Publisher: Springer Science & Business Media, 2012-08-30
Pages: 261
Language: en
ISBN_13:9783642180538
ISBN_10:3642180531
Subject: Technology & Engineering

Bone Aging and Osteoporosis: Recent Evidence Focusing on Plant-Based Natural Products

$The human skeleton undergoes a life-long remodeling process. Bone homeostasis requires a potential balance between bone-resorbing osteoclasts and bone-forming osteoblasts. With old age, bone homeostasis undergoes deregulation, and normal bone remodeling could not make bone mass stable, thus causing osteopenia and osteoporosis. Osteoporosis is a systemic bone disease characterized by reduced bone mass, degraded bone microstructure, increased bone fragility and raised risk of fracture. Osteoporosis is a frequently occurring and common disease in the aging population, especially in postmenopausal women and elderly men. The updated research found that one-third of women aged 60 to 70 suffer from osteoporosis; Two-thirds of women aged 80 years or older have osteoporosis. About 20-25% of women over 50 years of age have one or more vertebral fractures. Recent research evidence indicates that an increasing number of plant-based natural products (or secondary metabolites), such as polyunsaturated fatty acids, phytosterols, flavonoids, and other botanicals active compounds, have beneficial effects on the risk of osteoporosis. Compared with conventional therapies, plant-based natural products with thousands of years of medical use experience are gradually approved for clinical use due to fewer adverse reactions, low toxicity, high efficiency and good tolerance. Natural products have been an important source of inspiration for new drug development. However, most of the evidence regarding the anti-osteoporosis effects of natural products comes from in vitro and preclinical in vivo studies, and only a few natural products have been used clinically. All of these above-mentioned still require rigorously designed studies and further verification.$

جزئیات و درخواست

By Lingfeng Zeng, Ning Zhang, Wenhua Ling, Claudio Lucchiari
Publisher: Frontiers Media SA, 2024-03-08
Pages: 170
Language: en
ISBN_13:9782832545959
ISBN_10:2832545955
Subject: Medical

Osteoporosis in Older Persons

Pathophysiology and Therapeutic Approach

جزئیات و درخواست

By Gustavo Duque, Douglas P. Kiel
Publisher: Springer Science & Business Media, 2009-10-13
Pages: 201
Language: en
ISBN_13:9781846286971
ISBN_10:1846286972
Subject: Medical

Osteoporosis in Older Persons

Advances in Pathophysiology and Therapeutic Approaches

$This new edition includes the most up-to-date information about the pathophysiology and new therapeutic alternatives for osteoporosis of advanced age. It is written by investigators (clinicians and basic scientists) in the field of aging bone research. It was just recently that a new syndrome, osteoporosis of advanced age, was recognized as a new entity with its own pathophysiology and potential treatments. Unfortunately, and despite the fact that hip fractures are mostly a consequence of this process, and apart from the first edition of this book, there are few publications about this subject. The first edition of this book demonstrated that there is a need to understand the particular features of osteoporosis in older persons, which is the main aim of this book. The institutions where the authors are affiliated are highly recognized as the main centers in aging bone research. As an innovation, the second edition includes some aspects of muscle and bone interaction focusing of the impact of age-related muscle loss (sarcopenia) on the pathogenesis of falls and fractures in older persons. As in the previous edition, this book is expected to be the reference guide for geriatricians, gerontologists, and bone biologists as well as medical trainees in order to understand the mechanisms of senile osteoporosis with a practical approach to the treatment of its consequences.$

جزئیات و درخواست

By Gustavo Duque, Douglas P. Kiel
Publisher: Springer, 2016-07-11
Pages: 299
Language: en
ISBN_13:9783319259765
ISBN_10:3319259768
Subject: Medical

The Aging Skeleton

$The Aging Skeleton is a comprehensive and timely book on all aspects of the skeleton as it ages, including basic mechanisms and pathways as well as pathobiology. Chapters cover general aspects and models of aging, determinants and maintenance of peak bone mass, mechanisms of age-related bone loss, quantifiable manifestations of age-related bone loss, fractures, and therapeutics. Covers all aspects of the aging skeleton in one comprehensive volume Looks at the influence of genetics, nutrition, environment, hormones, and other factors on bone mass Provides a thorough discussion of fractures, one of the major consequences of the aging skeleton Reviews current therapeutic approaches and methods Written by internationally renowned authors and edited by leaders in the field Is the only book available on this subject$

جزئیات و درخواست

By Clifford Rosen, Julie Glowacki, John P. Bilezikian
Publisher: Elsevier, 1999-08-19
Pages: 667
Language: en
ISBN_13:9780080542379
ISBN_10:0080542379
Subject: Medical

Aging Bones

A Short History of Osteoporosis

جزئیات و درخواست

By Gerald N. Grob
Publisher: JHU Press, 2014-04-15
Pages: 305
Language: en
ISBN_13:9781421413181
ISBN_10:1421413183
Subject: Law

Osteoporosis

An Evidence-based Guide to Prevention and Management

$Until recently considered an inevitable part of aging, osteoporosis is typically diagnosed only after a serious complication such as a fracture. It is now possible, however, to diagnose high-risk patients beforehand. Easily performed noninvasive tests estimate bone mass, and patients at risk can be treated with new drugs whose efficacy for fracture reduction has been proven in clinical trials. Osteoporosis: An Evidence-Based Guide to Prevention and Management, the newest volume in the acclaimed ACP Women's Health series, addresses every important facet of this common disease. The latest scientific evidence and the extensive clinical experience of the authors provide essential information on the origins and progress of osteoporosis. Treatment options are thoroughly reviewed.$

جزئیات و درخواست

By Steven R. Cummings, Felicia Cosman, Sophie A. Jamal
Publisher: ACP Press, 2002
Pages: 305
Language: en
ISBN_13:9780943126951
ISBN_10:0943126959
Subject: Medical

Bone Loss and Osteoporosis

An Anthropological Perspective

$With the growing incidence of fragility fractures in Europe and North America over the last three decades, bone loss and osteoporosis have become active areas of research in skeletal biology. Bone loss is associated with aging in both sexes and is accelerated in women with the onset of menopause. However, bone loss is related to a suite of complex and often synergistically related factors including genetics, pathology, nutrition, mechani cal usage, and lifestyle. It is not surprising that its incidence and severity vary among populations. There has been increasing interest to investigate bone loss and osteoporosis from an anthropological perspective that utilizes a biocultural approach. Biocultural approaches recognize the inter-relationship between biological, cultural, and environmental variables. Anthropological studies also highlight the value of evolutionary and population approaches to the study of bone loss. These approaches are particularly suited to elucidate the multifactorial etiology of bone loss. The idea for this volume came out of a symposium organized by the editors at the 70th annual meeting of The American Association of Physical Anthropologists in Kansas City, Missouri. Many of the symposium participants, along with several additional leading scientists involved in bone and osteoporosis research, are brought together in this volume. Each chapter focuses on a different aspect of bone loss and fragility with a fresh and stimulating perspective.$

جزئیات و درخواست

By Sabrina C. Agarwal, Samuel D. Stout
Publisher: Springer Science & Business Media, 2011-06-28
Pages: 431
Language: en
ISBN_13:9781441988911
ISBN_10:1441988912
Subject: Social Science

Osteoporosis in Men

The Effects of Gender on Skeletal Health

$Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men. This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger – 8.5 x 11. This edition of Osteoporosis in Men brings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy. Brings together more eminent investigators and clinicians to interpret developments in this growing field Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy There is no book on the market that covers osteoporosis in men as comprehensively as this book$

جزئیات و درخواست

By Eric S. Orwoll, John P. Bilezikian, Dirk Vanderschueren
Publisher: Academic Press, 2009-11-30
Pages: 764
Language: en
ISBN_13:9780080923468
ISBN_10:0080923461
Subject: Medical

The Aging Spine

جزئیات و درخواست

By Max Aebi
Publisher: Springer Science & Business Media, 2005-02-23
Pages: 154
Language: en
ISBN_10:3540244085
ISBN_13:9783540244080
Subject: Medical

Nutrition and Osteoporosis

$Nutrition and Osteoporosis: Seeing Through a Glass, Darkly (1 Cor. 13:12) This volume of Advances in Nutritional Research deals with the present state of knowledge relative to the role of nutrition in the etiology of osteoporosis, one of the most serious degenerative diseases in the aging population. As a back drop for subsequent chapters on specific nutrients, Chapter 1 provides a com prehensive account of the gain and loss of bone throughout the life cycle, with emphasis on the architectural changes in later life that predispose to osteoporotic bone fractures. Chapter 2 documents the occurrence of aging bone loss through out human archeological history and Chapter 3 extends this documentation to all non-human vertebrate species so far examined, including primates living in the wild. It is apparent that a progressive loss of bone tissue is a normal accompaniment of aging among higher vertebrates. Whether it is a cause of bone fractures in animals, as it is in humans, is still unknown. It has also been established that there are significant differences in the frequency of osteoporotic fractures among human families, ethnic groups, national populations and diet cultures. Numerous studies have been carried out in an effort to explain these differences, and many of these deal with the possible effect of nutrition. Protracted controversies over the role of nutrition in the etiology of osteoporosis are reflected in the contents of several of the ensuing chapters.$

جزئیات و درخواست

By Harold H. Draper
Publisher: Springer Science & Business Media, 2013-06-29
Pages: 325
Language: en
ISBN_13:9781475790924
ISBN_10:1475790929
Subject: Technology & Engineering

Osteoporosis

Diagnosis, Prevention, Therapy

جزئیات و درخواست

By Reiner Bartl, Bertha Frisch
Publisher: Springer Science & Business Media, 2009-05-12
Pages: 313
Language: en
ISBN_13:9783540795278
ISBN_10:3540795278
Subject: Medical

Aging, Osteoporosis, and Dental Implants

جزئیات و درخواست

By George Albert Zarb
Publisher: Quintessence Publishing (IL), 2002
Pages: 280
Language: en
OTHER:UOM:39015051607334
Subject: Health & Fitness

Post-Menopausal Osteoporosis

$Osteoporosis is one of the most common bone disorders, characterised by weakened bones and resulting in increased chances of fractures. This book begins with an overview of the disorder and continues with discussion on pathogenesis, epidemiology and genetic factors. The effects of menopause and aging on bone health, as well as identifying risk factors contributing to fractures, are examined. The following sections discuss management of osteoporosis including surgery and non-pharmacologic and lifestyle approaches to reducing the risk of fractures. With contributions from specialists in the UK, Italy, USA, New Zealand and India, this practical guide includes 50 images and illustrations to assist learning. Key points: Practical guide to the causes, diagnosis, treatment and management of osteoporosis Covers non-pharmacologic and lifestyle approaches to reduce risk of fractures Contributions from specialists in the UK, Italy, USA, new Zealand and India Includes 50 images and illustrations$

جزئیات و درخواست

By Meeta
Publisher: JP Medical Ltd, 2013-04-30
Pages: 282
Language: en
ISBN_13:9789350900857
ISBN_10:9350900858
Subject: Health & Fitness

Skeletal Development and Remodeling in Health, Disease and Aging, Volume 1068

جزئیات و درخواست

By Mone Zaidi
Publisher: Wiley-Blackwell, 2006-06-23
Pages: 604
Language: en
OTHER:UVA:X030118191
Subject: Medical

Osteoporosis: Genetics, Prevention and Treatment

Genetics, Prevention and Treatment

جزئیات و درخواست

By John S. Adams, Barbara P. Lukert
Publisher: Springer Science & Business Media, 2012-12-06
Pages: 434
Language: en
ISBN_13:9781461551157
ISBN_10:1461551153
Subject: Medical

Osteoporosis

Hearing Before the Subcommittee on Aging of the Committee on...

Free Epub

جزئیات و درخواست

By United States. Congress. Senate. Committee on Labor and Human Resources. Subcommittee on Aging
1985
Pages: 268
Language: en
OTHER:UOM:39015039053700
Subject: Osteoporosis

The Aging Skeleton

Aspects of Human Bone Involution

جزئیات و درخواست

By Spencer Lee Rogers
Publisher: Charles C. Thomas Publisher, 1982
Pages: 124
Language: en
OTHER:UOM:39015004412014
Subject: Medical

Osteosarcopenia

$Falls, fractures, frailty, osteoporosis and sarcopenia are highly prevalent in older persons. While the concept of osteosarcopenia is new, it is a rapidly evolving and cross-disciplinary problem. Prevention and treatment are challenging and a combined therapeutic approach is needed. Osteosarcopenia provides evidence-based information on how to prevent and treat these conditions at multiple settings, including multiple illustrations, care pathways and tips to easily understand the pathophysiology, diagnostic methods and therapeutic approach to these conditions. This work evaluates the potential for a link between osteoporosis, sarcopenia and obesity. Presents diagnostic and therapeutic tips that facilitate the design and implementation of new care pathways, impacting the wellbeing of our older population Provides cross-disciplinary understanding by experts from the bone/osteoporosis field and the muscle/sarcopenia field Covers muscle and bone biology, mesenchymal stem cells, age-related changes and cross-talk between muscle, fat and bone, falls and fracture risk, glucose metabolism, diagnosis, imaging, and genetics of osteosarcopenia$

جزئیات و درخواست

By Gustavo Duque, Bruce R. Troen
Publisher: Elsevier, 2022-03-04
Pages: 350
Language: en
ISBN_13:9780128204207
ISBN_10:0128204206
Subject: Medical

Multidisciplinary Approach to Osteoporosis

From Assessment to Treatment

جزئیات و درخواست

By Andrea Lenzi, Silvia Migliaccio
Publisher: Springer, 2018-09-04
Pages: 330
Language: en
ISBN_13:9783319751108
ISBN_10:3319751107
Subject: Medical

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