Customized Artificial Implants: Bionic Design and Multiscale Evaluation
Description:... Artificial implants have been commonly used to replace or fix damaged tissue in orthopedics. However, due to the inter-individual differences and the complexities of anatomical structures and load conditions, traditional implants cannot meet the clinical requirements. In recent years, questions relating to customized artificial implants have been getting more and more attention from the research community. Challenges to implementing precision design and evaluation arise not only from the design need of considering bionic structures, kinematical function, mechanical performances, and biological functional similarity but also from the multiscale comprehensive evaluation, the latter involves biomechanics and biotribology of musculoskeletal systems from macro musculoskeletal multibody dynamics to micromechanics of porous structures. Established analysis technologies such as musculoskeletal multibody dynamics modeling and neuromusculoskeletal modeling are being well developed and evolved through combining/coupling with finite element analyses and, more recently, by novel artificial intelligence approaches.
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