Single-cell Sequencing and Methylation

Methods and Clinical Applications

• Author(s): Buwei Yu, Jiaqiang Zhang, Yiming Zeng, Li Li, Xiangdong Wang,
• Publisher: Springer Nature
• Pages: 247
• ISBN_10: 9811544948
  ISBN_13: 9789811544941
  
• Language: en
• Categories: Science / Life Sciences / Molecular Biology , Science / Life Sciences / Anatomy & Physiology , Medical / Oncology / General , Medical / Research , Medical / General ,

Description:...

With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.