Subthalamic and Thalamic Stereotactic Recordings and Stimulations in Patients with Intractable Epilepsy
Description:... Various subcortical structures in the brain are thought to be important
in genesis or propagation of seizures. Deep Brain Stimulation (DBS) of
these structures aims to influence these key “pacemaker” areas in the
brain and is gaining increasing interest as a possible new surgical
modality for treatment of patients with intractable epilepsy.
Based on this background, this volume brings together the experienceof the Zurich Epilepsy Surgery Center with stereotactic recordings and
stimulations of various subcortical nuclei, with special reference to
the Forel H fields, the thalamic nuclei and the periaqueductal gray
matter. This volume also addresses the important issues of DC
recording/polarisation and of biochemical measurement of excitatory and
inhibitory transmitters released in the primary epileptogenic area
during epileptic discharges.
This book is destined to improve understanding of the involvement ofsubcortical structures in seizure genesis or propagation in a time whenexhaustive invasive presurgical evaluation is diminishing because of
the today’s availability of modern non-invasive imaging technique.
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