Cell-Based Biosensors

• Author(s): Jaroslav Racek,
• Publisher: CRC Press
• Pages: 107
• ISBN_10: 1566761905
  ISBN_13: 9781566761901
  
• Language: en
• Categories: Technology & Engineering / Materials Science , Medical / Biotechnology , Technology & Engineering / Biomedical ,

Description:... SOME ADVANTAGES OF CELL-BASED BIOSENSORS:
Isolation, purification, and immobilization of enzymes are often very difficult; these can be omitted with cell-based biosensors.
Some enzymes can lose their activity during isolation or immobilization; this risk is eliminated by the use of whole cells.
Enzymes in the cell's natural environment are usually extremely stable.
Multi-step enzyme reactions in intact cells can be used, making it possible to avoid the preparation of complicated artificial multi-enzyme systems.
Coenzymes and activators are often present in the cells, and thus, it is not necessary to add them into the system; the cell itself usually cares for their effective regeneration.