Acute and Hereditary Coagulation Disorders
Description:... Coagulation disorders can have a variety of causes and may lead to either an increased risk of excessive bleeding or an increased risk of thromboembolic events. Both types of coagulation disorders can be life-threatening and require immediate therapy. Major bleeding is often triggered by an acute cause, such as severe trauma or peripartum hemorrhage (PPH) . The high rate of pre-existing intake of anticoagulants, such as DOACS or Vitamin-K antagonists, can also induce or even aggravate bleeding events, for example in cerebral hemorrhage or traumatic brain injury (TBI). Hereditary causes, such as the congenital Factor XIII deficiency or hemophilia, can also trigger a clinically relevant hemorrhage however, hereditary coagulation disorders are more often associated with thromboembolic events.
Show description