The Ubiquitin-Proteasome System and Disease

• Author(s): R. John Mayer, Aaron J. Ciechanover, Martin Rechsteiner,
• Publisher: John Wiley & Sons
• Pages: 258
• ISBN_10: 3527620303
  ISBN_13: 9783527620302
  
• Language: en
• Categories: Science / Life Sciences / Cell Biology , Science / Life Sciences / Molecular Biology , Science / Chemistry / General , Science / Chemistry / Organic ,

Description:... This final volume in the series focuses on malfunctions of the ubiquitin-proteasome system and their role in human disease.
The editors and authors represent unmatched expertise, comprising virtually all the top scientists in the field, including the pioneers of protein degradation research.
From the contents:
* Ubiquitin and cancer
* Ubiquitin and liver cancer
* Muscle atrophy
* Aggresomes and human disease
* Parkin and neurodegeneration
* Chronic neurodegenerative diseases
* Parkinson's disease
* Ubiquitin and viruses
* Druggability of the ubiquitin-proteasome system
Required reading for molecular and cell biologists, as well as physiologists with an interest in the topic.