Primary Immunodeficiency Diseases
A Molecular and Cellular Approach
- Author(s): Hans D. Ochs,, C. I. Edvard Smith,, Jennifer M. Puck,,
- Publisher: OUP USA
- Pages: 911
- ISBN_10: 0195389832
ISBN_13: 9780195389838
- Language: en
- Categories: Medical / General , Medical / Infectious Diseases , Medical / Hematology , Medical / Immunology , Medical / Pediatrics , Medical / Rheumatology , Medical / Genetics ,
Description:... Features: --Updated with new diagnostic and treatment options --Includes discoveries of new genes that related to immunodeficiency disorders --Provides readers with the historic and scientific background, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases --An authoritative resource on this increasingly important area Primary immunodeficiency diseases, first recognized 60 years ago, are inherited disorders that affect human adaptive and innate immunity. In most cases, affected individuals experience recurrent infections, but they may also suffer from autoimmune diseases and malignancies. This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases. With up-to-date diagnostic tools and therapeutic options -- from prophylactic anti-infective measures to hematopoietic stem cell transplantation and gene therapy -- this volume will remain an authoritative resource on this increasingly important area. Hans D. Ochs, MD, Dr.med, is Professor of Pediatrics, University of Washington and Seattle Children's Research Institute, Seattle, WA. C. I. Edvard Smith, MD, PhD, is Professor of Molecular Genetics, Karolinska Institutet, Stockholm, Sweden. Jennifer M. Puck, MD, is Professor of Pediatrics and Medical Director of the Pediatric Clinical Research Center, University of California, San Francisco. Publisher's note.
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