Generating and Sustaining Stable Autoantigen-specific CD4 and CD8 Regulatory T Cells in Lupus
Description:... ...[T]his research topic invites contributions from experts related to, but not limited to, the following categories: 1) Lupus T cell epitopes with known Treg inducing ability/tolerogenicity; 2) Tolerogenic delivery of epitopes, such as in nanoparticles; 3) Treg stability maintenance mechanisms, such as molecular and epigenetic mechanisms, metabolic mechanisms; 4) Potentiate peptide tolerance by IL-2 and other adjunct therapy such as IL-2 in low dose, or in nanoparticles, IL-2 muteins, or pegylated IL-2, and other agents."--from submission guidelines
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