Bone and joint infection: past, present, and future
Description:... Bone and joint infections (BJI) cause serious morbidity and pose significant management challenges. They may cause acute sepsis with bone and joint destruction, discharging wounds, chronic pain, and permanent disability. With increasing age and expanding populations, bone and joint infections, especially those involving devices, will have a growing impact on healthcare resources. Specifically, one typical type of BJI, periprosthetic joint infection, is even more difficult to manage. Although the incidence of PJI is not high, the diagnosis is difficult; the treatment is complicated, and the efficacy is uncertain. Patients usually need to undergo multiple operations with long-term antibiotic treatment.
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