Vector-borne diseases have increasingly emerged as significant causes of human illnesses worldwide, largely due to environmental changes (deforestation), population movements (migration and travelling), international trades, and buildup of drug resistance. These are presenting major challenge to the efficacy and use of conventional tools for controlling vector-borne diseases. Therefore, use of microbial approach for the control of vector-borne diseases is gaining importance. This book comprehensively reviews vector-borne diseases and their microbial control, emphasizing majorly on ecofriendly ways of microbial control